Reprinted: Clinical and Imaging Scoring of Peritoneal Carcinomatosis

Peritoneal cancer is primarily classified into two types: primary and secondary. Secondary peritoneal cancer accounts for more than 90% of clinical cases and is most often caused by metastasis from tumors such as gastric cancer, colorectal cancer, and ovarian cancer. Primary peritoneal cancer is rare and predominantly consists of high-grade serous carcinoma; its clinical presentation is insidious, with early symptoms typically limited to abdominal distension, abdominal pain, or mild ascites.

2026-05-28

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Pharmacokinetics of cisplatin in the systemic versus hyperthermic intrathoracic or intraperitoneal chemotherapy

Objective To compare the pharmacokinetics and adverse effects of cisplatin administered via intravenous infusion

2025-09-03

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Good Doctor Animal Experiment | Animal experiment comparing the flow rate and temperature of intraperitoneal hyperthermic perfusion chemotherapy with three different catheterization methods August 2022 Modern Oncology Medicine - Volume 30, Issue 15

Compare the differences in perfusion flow rate and intraperitoneal temperature between surgical catheter placement and medical peritoneal puncture catheter placement in hyperthermic intraperitoneal chemotherapy (HIPEC) through animal experiments.

2025-09-03

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Good Doctor Animal Experiment | Safety Study of Intracavitary Circulatory Hyperthermic Perfusion Chemotherapy June 2012 Chinese Journal of Clinical Oncology - Vol. 39, No. 22

To observe the effects of different temperatures during cavity circulatory thermal perfusion chemotherapy (CCTP) on the vital signs and abdominal organs of experimental dogs, and to determine the appropriate temperature for CCTP in experimental animals. Method: Dogs were used as experimental animals, and indicators were measured at abdominal cavity temperatures of 41, 42, and 43°C respectively.

2025-09-03

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Emerging treatment strategies for pleural dissemination or pleural recurrence of thymoma - surgery combined with intrapleural hyperthermic chemotherapy

Emerging treatment strategies for pleural dissemination or pleural recurrence of thymoma - surgery combined with intrapleural hyperthermic chemotherapy

Thymoma is the most common type of tumor in the anterior mediastinum. The pleura is a hotspot for thymoma metastasis, known as the "host site"; pleural dissemination is a special mode of metastasis for thymoma. Pleural metastasis of thymoma may already exist at the initial diagnosis, representing stage M1a thymoma; or it may appear during follow-up after treatment, representing pleural recurrence (TPR). Surgery is an important treatment method for patients with pleural dissemination or TPR thymoma. Currently, there is no unified opinion on surgical approaches and methods. Simple surgery is difficult to achieve truly complete resection of pleural dissemination or TPR thymoma. Intraoperative hyperthermic intratumoral chemotherapy (HITOC) is an effective supplementary treatment, but internationally, the selection of HITOC regimens and setting of conditions are still under exploration; previous studies were mainly small sample, retrospective, and non-controlled studies with many confounding factors and limited clinical experience. This article summarizes and analyzes the diagnosis and treatment progress of pleural dissemination or TPR thymoma with surgery combined with HITOC, providing a theoretical basis for selecting reasonable treatment methods and formulating individualized treatment strategies.

2025-07-30

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2025 Expert Consensus on the Design of Interventional Clinical Studies for Malignant Pleural Effusion (2025 Edition)

Expert Consensus on the Design of an Interventional Clinical Study of Malignant Pleural Effusion

2025-07-10

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CACA China Integrated Diagnosis and Treatment Guidelines for Peritoneal Tumors - 2025 Edition

Peritoneal tumors are mainly classified as primary and secondary. Primary tumors originate from the peritoneum; common types include primary peritoneal cancer (Müllerian-type epithelial tumors, mainly serous carcinoma) and malignant peritoneal mesothelioma (MPM). Secondary tumors include various metastatic cancers, peritoneal sarcomatosis (PS), pseudomyxoma peritonei (PMP), and gliomatosis. Clinically, metastatic and epithelial malignant peritoneal tumors are more common, while primary and mesenchymal tumors are relatively rare and considered rare diseases.

2025-07-10

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Chinese Expert Consensus on the Diagnosis and Treatment of Colorectal Cancer Peritoneal Metastasis (2025 Edition)

Colorectal cancer is one of the most common malignant tumors in China, ranking second and fourth in incidence and mortality rates among all malignant tumors, respectively. Metastasis and recurrence are the main causes of death in patients with colorectal cancer. The peritoneum is a common site of colorectal cancer metastasis, second only to liver and lung metastasis, but its prognosis is far worse than that of liver and lung metastasis.

2025-07-10

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【New Law】Application and Key Points of Thoracic Thermal Perfusion Chemotherapy in Thoracic Treatment

Malignant pleural effusions (MPEs) are mainly seen in patients with advanced lung cancer (37.5%), breast cancer (16.8%), lymphoma (11.5%), genitourinary malignancies (9.4%), and gastrointestinal malignancies (6.9%); the median overall survival time for patients with MPEs and pleural metastases is 3-4 months.

2025-07-10

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