Chinese Expert Consensus on the Diagnosis and Treatment of Platinum-Resistant Recurrent Ovarian Cancer (2025 Edition)

Among gynecological malignancies, ovarian cancer has the most grim prognosis, primarily due to its high recurrence risk after treatment. Multiple recurrences lead to increased drug resistance. Recurrent ovarian cancer is classified into platinum-sensitive and platinum-resistant types, and treatment strategies depend on the patient's sensitivity to platinum-based chemotherapy. For patients with platinum-sensitive recurrent ovarian cancer, the use of platinum-based chemotherapy combined with targeted therapy (such as PARP inhibitors or bevacizumab) has been shown to prolong survival.

2025-07-10

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Science Translational Medicine research paper: Hyperthermia reshapes the tumor microenvironment and proposes a new strategy for combined treatment of ovarian cancer

Hyperthermic intraperitoneal chemotherapy (HIPEC) has been used to treat gastric cancer, but its efficacy in patients with peritoneal metastasis of ovarian cancer remains unclear, hindering the development of rational combination therapies based on hyperthermia (HT).

2025-07-09

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Retrospective analysis on the safety of 5,759 times of bedside hyperthermic intra-peritoneal or intra-pleural chemotherapy (HIPEC)

The current study was designed to analyze safety of the bedside hyperthermic intra-pleural or intra-peritoneal chemotherapy (HIPEC) from September 2007 to July 2015. Total of 5,759 times of bedside HIPEC in 985 cases of malignant pleural or peritoneal carcinomatosis were analyzed.

2025-07-08

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Clinical study on continuous constant temperature circulation hot infusion therapy for malignant ascites.

Objective: To explore the efficacy of continuous circulating hyperthermic intraperitoneal chemotherapy (HIPEC) at a temperature of 42-43°C for malignant ascites. Method: 45 patients with malignant ascites were randomly divided into two groups. The observation group consisted of 22 patients who underwent conventional puncture to establish a double-channel circulation, first performing peritoneal lavage to replace the intraperitoneal perfusion fluid, and finally maintaining 2500-3500 ml. The continuous circulation at a temperature of 42-43°C began 3-5 minutes later.

2022-08-26

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Understanding the Main Characteristics of Cancer Cells in Tumor Knowledge

A tumor (tumor, neoplasm) is a genetic disease, but it is not hereditary; it refers to the change in genes under the influence of tumorigenic factors, losing normal regulation of its growth, leading to abnormal proliferation. It can be divided into two main categories: benign and malignant tumors.

2022-08-26

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Application of Intraperitoneal Hyperthermic Chemotherapy after Surgery for Gastrointestinal Malignancies

Discuss the efficacy of intraperitoneal hyperthermic chemotherapy after surgery for gastrointestinal malignancies. Method: Select 60 patients with stage II to IV gastrointestinal malignancies after surgery, with 32 cases as the treatment group receiving intraperitoneal hyperthermic chemotherapy + intravenous chemotherapy, and 28 cases as the control group receiving conventional intravenous chemotherapy. Results: The intraperitoneal recurrence rate and metastasis rate in the treatment group were significantly lower than those in the control group (P

2022-08-26

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Expert consensus on cytoreductive surgery combined with intraperitoneal hyperthermic chemotherapy for peritoneal surface tumors

Expert consensus on cytoreductive surgery combined with intraperitoneal hyperthermic chemotherapy for peritoneal surface tumors

2022-08-26

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Safety experimental study of intraperitoneal hyperthermic perfusion chemotherapy - Liu Wenchao 2012 (Li Wei)

Safety Experimental Study of Intraperitoneal Circulation Hyperthermic Perfusion Chemotherapy - Liu Wenchao 2012 (Li Wei) Safety Experimental Study of Intraperitoneal Circulation Hyperthermic Perfusion Chemotherapy - Liu Wenchao 2012 (Li Wei) Safety Experimental Study of Intraperitoneal Circulation Hyperthermic Perfusion Chemotherapy - Liu Wenchao 2012 (Li Wei)

2022-08-26

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Clinical analysis of 110 cases of gastric cancer peritoneal carcinoma treated with tumor cell reduction surgery combined with intraperitoneal hyperthermic chemotherapy.

Clinical analysis of 110 cases of gastric cancer peritoneal carcinoma treated with tumor cell reduction surgery combined with intraperitoneal hyperthermic chemotherapy.

2022-08-26

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